Overview
5-MeO-DMT is a relatively short-acting psychedelic drug and the ‘trip’ usually lasts less than 30 minutes when smoked, and up to 45 minutes when insufflated. When vaporized and inhaled the effects begin almost instantaneously, which means it is very important to be in a safe and comfortable environment to avoid accidents
Users often report overwhelmingly intense experiences which can sometimes be difficult to remember. Accounts of mystical union, feelings of non-duality and experiences of a transpersonal nature are not uncommon. Often uncomfortable bodily sensations such as a rapid heart rate, nausea and pressure in the chest can be present.
The alterations to perception as a result of taking 5-MeO-DMT often include auditory and visual hallucinations, internal scenes, time perception distortions and cognitive and/or emotional shifts
5-MeO-DMT in moderate to high doses will often leave the user incapacitated, so it is important to have someone present to prevent an individual from injuring themselves if they start moving around. Because of this, it is also advisable to be aware of the environment in which it is consumed, avoiding obvious hazards such as bodies of water and steep drops.
Occasionally, effects can vary from abnormal vocalisations and unusual body movements to complete unresponsiveness. Therefore, the person accompanying a 5-MeO-DMT user should know how to place someone in the recovery position, as vomiting is sometimes reported. Bear in mind that unconsciousness, along with breathing difficulties, is a sign of overdose and should be monitored.
Although 5-MeO-DMT is sometimes used in South American Ayahuasca recipes, it is generally considered dangerous to mix with any MAOI.
As 5-MeO-DMT is active in doses from as small as 3mg, weighing the dose carefully with a precise scale is important to avoid accidental overdose.
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